Pharmacological Approaches for Pain
There are several pharmacological interventions that may be accustomed manage pain in arthritis. However, in choosing the acceptable approach, the practitioner must take into account to consider the efficacy. Adverse side effects, dosing frequency, patient preference, and cost in choosing medication for pain management. When a patient develops the primary signs of inflammatory arthritis, the most priority is symptom relief, with pain being the cardinal sign of inflammation that patients most wish to facilitate with. However, it has become more and more clear that for inflammatory arthropathies like RA merely treating the symptoms with non- Steroidal anti- inflammatory drugs (NSAIDs) or analgesics in adequate, because features of the disease that lead to damage to the joints, and then to disability will carry on unchecked. In addition to symptoms –relieving drugs, patients also need disease-modifying pain drugs that have been demonstrated to slow down or stop the damaging aspects of disease There are two aims in the pharmacological treatment; firstly to reduce inflammation or modulate the auto immune response and secondly to modulate the pain response. Medications are thought-about in 5 classes: simple analgesics, non-steroidal anti-inflammatory drugs (NSAIDs), Disease modifying anti-rheumatic-drugs (DMARD’S), Steroids, Biologics and other relevant Adjuvant analgesics (ex. antiepileptic and antidepressants used for pain relief).
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